Shin Nekketsu Kōha: Kunio-tachi no Banka (新・熱血硬派 くにおたちの挽歌 The New Hot-Blooded Tough Guy: The Eulogy of Kunio and Co.?) is a belt-scrolling action game released by Technos Japan Corp. exclusively in Japan for the Super Famicom in 1994. It was the fourth game in the Kunio-kun series released for the Super Famicom and was developed by Almanic.

Shin Nippon Pro Wrestling: Chou Senshi in Tokyo Dome is a Sports game, published by Varie, which was released in Japan in 1993.

Shounen Ninja Sasuke is an action-adventure game released by Sunsoft for the Super Nintendo Entertainment System in 1994. The game was supposed to be released in English as Boy Ninja Sasuke.

Side Pocket (Japanese: サイドポケット, Hepburn: Saido Poketto?) is a pocket billiards video game originally released into arcades by Data East in 1986. The arcade version was eventually ported to six home console platforms and two sequels to the game were produced. G-Mode currently owns the intellectual property rights to the Side Pocket series, and licenses these games globally.

Experience life as an ant: fight for queen and colony, face hungry spiders and menacing hordes of enemy ants, eat yummy caterpillars, and drive those yucky humans out of the house! Based on real ants, SimAnt has the depth of play and serious gaming challenge to really drive you buggy. SimAnt is about the closest you'll get to being an ant without growing more legs, removing your brain and living in a hole in the ground.

SimCity 2000 (SC2K) is a city-building simulation video game and the second installment in the SimCity series. SimCity 2000 was first released by Maxis in 1994 for computers running Apple Macintosh Operating System. It was later released on the Amiga, DOS & Microsoft Windows, followed by a release for OS/2. In 1995, SimCity 2000 won "Best Military or Strategy Computer Game" Origins Award.

SimTown is a 1995 video game published by Maxis, much like the best selling SimCity but on a smaller scale. SimTown allows the player to construct a town consisting of streets, houses, businesses and parks and then control the people in it. SimTown was one of the many 'Sim' spin-offs at the time, and was targeted more towards children.The Super Famicom/Super Nintendo Entertainment System version of SimTown is called SimCity Jr. (シムシティJr.?). It was published by Imagineer.

Sink or Swim is a video game that was released in 1993 for the PC under the DOS environment. Developed by Zeppelin Games Limited, it was an action/puzzle game very similar in style to Lemmings. Versions also made their way onto the Amiga and the SNES. The Sega Mega Drive/Genesis and Game Gear versions are known as S.S. Lucifer: Man Overboard!. The game was the first demo disk attached to PC Gamer magazine.

Sküljagger: Revolt of the Westicans is a 2D action platformer video game that was released exclusively for the North American Super Nintendo Entertainment System in 1992.

Slayers (スレイヤーズ, Sureiyāzu?) is a Japanese comic fantasy media franchise originating in a series of over 52 light novels written by Hajime Kanzaka and illustrated by Rui Araizumi. The novels had been serialized in Dragon Magazine, and were later adapted into several manga titles, televised anime series, anime films, OVA series, role-playing video games, and other media. Slayers follows the adventures of teenage sorceress Lina Inverse and her companions as they journey through their world. Using powerful magic and swordsmanship they battle overreaching wizards, demons seeking to destroy the world, and an occasional hapless gang of bandits. The anime series is considered to be one of the most popular of the 1990s.

Smart Ball is an Action-adventure game for the Super Nintendo Entertainment System, known as Jelly Boy (ジェリーボーイ?) in Japan. A sequel called Jelly Boy 2 (ジェリーボーイ2?) was in production, but was never actually released.