Shadowrun is a cyberpunk-fantasy action role-playing video game for the Super Nintendo Entertainment System (SNES), adapted from the tabletop role-playing game Shadowrun by FASA. The video game was developed by Australian company Beam Software and first released in 1993 by Data East.The game is loosely based on the novel Never Deal with a Dragon by Shadowrun co-creator Robert N. Charrette and set in the year 2050. The player takes on the role of Jake Armitage, a man suffering from amnesia after having been critically wounded by assassins. The plot then follows Jake as he attempts to uncover his own identity and the identity of the mysterious figure who wants him dead, and eventually complete his mission. Harebrained Schemes' 2013 Shadowrun Returns links the stories of this game and of Shadowrun for the Sega Genesis.A project to adapt Shadowrun for the SNES had a turbulent history between 1989 and 1993, including having been halted in mid-development before being resumed in late 1992 under a tight deadline. Its eventual lead designer was Paul Kidd, creator of Beam Software's 1992 Nightshade, elements and a feel of which he then carried on to Shadowrun. The game was a critical success, winning a number of industry awards, but was a commercial failure nevertheless. It was retrospectively acclaimed by several publications as an "ahead of its time" milestone in the history of the role-playing genre for the consoles and credited for having pioneered film noir style in video games.

Shanghai is a computer game developed by Activision in 1986 for the Amiga, Macintosh and Apple IIGS and also the Sega Master System.A sequel to this game was entitled Shanghai II: Dragon's Eye and was released on the Sega Genesis and Super NES. The former was also re-released on the Wii Virtual Console in the PAL regions on November 27, 2009 and in North America on January 11, 2010, which was later delisted at the end of 2013.

Shaq Fu is a 2D fighting game released on the Sega Mega Drive/Genesis and Super Nintendo game platforms on October 28, 1994. It was ported to the Amiga, Game Gear and Game Boy platforms in 1995. The game was published by Electronic Arts and developed by the now-defunct Delphine Software International. It features former professional basketball player Shaquille O'Neal (also known as Shaq) as a playable character. It is considered one of the worst video games of all time. A sequel, Shaq-Fu: A Legend Reborn, is in development.

Shien's Revenge, known in Japan as Shien: The Blade Chaser (紫炎～ザ・ブレイドチェイサー Shien ze Bureido Cheeisaa?), is an action game released for the Super Nintendo Entertainment System in 1994. It was the first video game designed by the famous manga and anime artist Go Nagai.

New Mobile Report Gundam Wing: Endless Duel (新機動戦記ガンダムＷ Ｅｎｄｌｅｓｓ Ｄｕｅｌ?) is a head-to-head fighting game released exclusively in Japan in 1996. It was the first video game to be based on the Mobile Suit Gundam Wing anime series, and has never been released outside of Japan. The developers have used the same engine as previously used in another game, Mighty Morphin Power Rangers: The Fighting Edition, but with some improvements added exclusively to this game.

Shin Megami Tensei (Japanese: 真・女神転生, literally "True Goddess Reincarnation") is a role-playing video game from Atlus that was originally released on October 30, 1992 for the Super Famicom. Loosely based on Megami Tensei, a novel and Famicom game series in Japan, Shin Megami Tensei would be the first of many titles in the franchise released by Atlus. A direct sequel, Shin Megami Tensei II, was released in 1994. A third game, Shin Megami Tensei: Nocturne, was released in 2003. The most recent installment, Shin Megami Tensei IV, was released in 2013. Two non-numbered titles, Shin Megami Tensei if... and Shin Megami Tensei: Strange Journey, were released in 1994 and 2009, respectively. Shin Megami Tensei has grown a large and loyal following around the world with additional game titles for consumer consoles and handheld systems. Previously unavailable in English (except for an unofficial fan-translated patch of the Super Famicom version, released on June 30, 2002), a localized iOS version was released in North America on March 18, 2014.

Shin Megami Tensei II (Japanese: 真・女神転生II, Hepburn: Shin Megami Tensei Tsū?) is a video game and direct sequel to Shin Megami Tensei for the Super Famicom released on March 18, 1994 in Japan. It was later remade for PlayStation in 2002, and then for Game Boy Advance in 2003. It is a role-playing video game and part of the Megami Tensei series. Similar to most games in the series, the player is able to persuade demons to join the main characters battle party.The game was only released in Japanese, although unofficial fan translations to English exist.

Shin Nekketsu Kōha: Kunio-tachi no Banka (新・熱血硬派 くにおたちの挽歌 The New Hot-Blooded Tough Guy: The Eulogy of Kunio and Co.?) is a belt-scrolling action game released by Technos Japan Corp. exclusively in Japan for the Super Famicom in 1994. It was the fourth game in the Kunio-kun series released for the Super Famicom and was developed by Almanic.

Shin Nippon Pro Wrestling: Chou Senshi in Tokyo Dome is a Sports game, published by Varie, which was released in Japan in 1993.

Shodai Nekketsu Kouha Kunio-Kun is a Role-Playing game, developed and published by Technos, which was released in Japan in 1992.

Shounen Ninja Sasuke is an action-adventure game released by Sunsoft for the Super Nintendo Entertainment System in 1994. The game was supposed to be released in English as Boy Ninja Sasuke.

What would you do if you were emperor? With Sid Meyer's Civilization, you are the emperor. You control your own personal civilization. And build it any way you want. Don't like schools? Don't build any. Think the Romans were crude? Wipe them out. And when your advisors tell you what to do, you tell them where to go. Attack your enemies like a ruthless warlord. And if they're really a pain, make'em. You've got the power to take on the greatest leaders in history.

Side Pocket (Japanese: サイドポケット, Hepburn: Saido Poketto?) is a pocket billiards video game originally released into arcades by Data East in 1986. The arcade version was eventually ported to six home console platforms and two sequels to the game were produced. G-Mode currently owns the intellectual property rights to the Side Pocket series, and licenses these games globally.

Experience life as an ant: fight for queen and colony, face hungry spiders and menacing hordes of enemy ants, eat yummy caterpillars, and drive those yucky humans out of the house! Based on real ants, SimAnt has the depth of play and serious gaming challenge to really drive you buggy. SimAnt is about the closest you'll get to being an ant without growing more legs, removing your brain and living in a hole in the ground.

SimCity (SNES) was the first console game in the SimCity series, and one of the launch titles for the Super Famicom/Super Nintendo Entertainment System in North America. It was developed by Nintendo EAD under license from Maxis and published by Nintendo in 1991.